Successful transplantation of organs from a donor
who died from acute cocaine intoxication
by
Caballero F, Lopez-Navidad A, Gomez M, Sola R.
Department of Organ & Tissue Procurement for Transplantation,
Hospital de la Santa Creu i Sant Pau,
Barcelona, Liver Transplantation Unit,
Hospital Juan Canlejo,
A Coruna, Kidney Transplantation Unit & Nephrology Service,
Fundacion Puigvert, Barcelona, Spain.
Clin Transplant 2003 Apr;17(2):89-92
ABSTRACTOne to two percent of the general population of western countries are regular consumers of cocaine, 10% being sporadic consumers. This proportion increases considerably in the population age groups which are most frequently organ donors. Cocaine may directly cause brain death, or be present in those with brain death who died from other causes, especially head trauma. We present a 30-yr-old female donor, a regular consumer of inhaled cocaine, who died of brain anoxia after cocaine inhalation. Twenty-five hours after cocaine inhalation, the liver and kidneys were removed for transplantation. The liver was transplanted to a patient with acute hepatocellular failure caused by isoniazids, and the kidneys to two recipients with renal polycystosis. Toxicity attributable to the cocaine was not observed in any of the three recipients. All three grafts presented immediate function, and the clinical evolution of all three recipients and the function of all three grafts were excellent during the 5 yr of follow-up. The serum creatinines of the two kidney recipients 5 yr from transplantation were 76 and 72 &mgr;mol/L, respectively.Users
History
Twin study
Mu and kappa
Quails on coke
Crack and crime
Drug education?
Prenatal cocaine
Dopaminergic flies?
Dopaminergic agents
Coca leaves/cocaine
Cocaine immunization
The coke-craving brain
Cocaine and methylphenidate
Cocaine, dopamine, noradrenaline and serotonin
Sigma antagonists in the treatment of cocaine addiction
Do sigma1 agonists like igmesine make cocaine more rewarding?
01 02 03 04 05 06 07 08 09 10 11 12
13 14 15 16 17 18 19 20 21 22 23 24
Refs
HOME
HedWeb
cannabis-marijuana.com
Future Opioids
BLTC Research
Wirehead Hedonism
Paradise-Engineering
Utopian Pharmacology
The Hedonistic Imperative
When Is It Best to Take Crack Cocaine?
The Good Drug Guide
The Responsible Parent's Guide To
Healthy Mood Boosters For All The Family
